383 Upper airway pathology in children with cystic fibrosis (CF)
نویسندگان
چکیده
منابع مشابه
CYSTIC FIBROSIS Airway remodelling in children with cystic fibrosis
Background: The relationship between airway structural changes and inflammation is unclear in early cystic fibrosis (CF) lung disease. A study was undertaken to determine changes in airway remodelling in children with CF compared with appropriate disease and healthy controls. Methods: Bronchoalveolar lavage and endobronchial biopsy were performed in a cross-sectional study of 43 children with C...
متن کاملAirway remodelling in children with cystic fibrosis.
BACKGROUND The relationship between airway structural changes and inflammation is unclear in early cystic fibrosis (CF) lung disease. A study was undertaken to determine changes in airway remodelling in children with CF compared with appropriate disease and healthy controls. METHODS Bronchoalveolar lavage and endobronchial biopsy were performed in a cross-sectional study of 43 children with C...
متن کاملPrevalence of Cystic Fibrosis Trans-membrane Conductance Regulator Gene common mutations in children with cystic fibrosis in Isfahan, Iran
Background: Cystic fibrosis (CF) is the most common lethal genetic disorder of Cystic Fibrosis Trans-membrane Conductance (CFTR) Regulator gene mutations. We aimed to investigate common mutations in CF patients and to assess its possible relationship with clinical presentations. Materials and Methods: This cross sectional study was conducted on 36 CF patients who were referred to a tertiary ped...
متن کاملReduced upper airway nitric oxide in cystic fibrosis.
Nitric oxide (NO) produced within the respiratory tract is detectable in exhaled and nasal air. Its synthesis may be induced by inflammatory cytokines and reduced by glucocorticoids. Increased concentrations have been found in asthma and bronchiectasis. In this study, NO concentrations were determined in 63 children with cystic fibrosis, of whom 13 were on inhaled steroids (mean age 13.3 years)...
متن کاملCystic fibrosis presenting as acute upper airway obstruction.
A 2 year old girl undergoing investigation for recurrent respiratory infections and failure to thrive presented acutely with neck and face swelling, tongue protrusion, and extreme difficulty in breathing. Examination showed extensive surgical emphysema over her chest, neck and face confirmed on the chest radiograph, which also revealed a pneumomediastinum (fig 1). While being prepared for emerg...
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ژورنال
عنوان ژورنال: Journal of Cystic Fibrosis
سال: 2011
ISSN: 1569-1993
DOI: 10.1016/s1569-1993(11)60395-0